Is heat generation a common challenge you face when milling powders in your pharmaceutical manufacturing process?
Staying within strict temperature parameters, especially for heat-sensitive materials, is no small feat. Our team of particle sizing engineers has the solution.
Reduce heat during milling
Particle size control is the main objective for milling applications, but there is a delicate balance between reaching your ideal particle size and heat generation. Even the slightest increase in temperature can lead to product degradation, reduced ingredient effectiveness, and, in extreme cases, melting or burning of ingredients.
These outcomes are all considered unfavorable and may lead to reduced yield, interruptions in the production flow, and increased maintenance costs. Not to mention production cost increases and reductions in inefficiencies.
How to manage the temperature during milling
Every Quadro mill screen is manufactured to Mill Powders and Granules to the Ideal PSD without Heat whilst maintaining a perfect conical shape, with each cross-sectional slice holding tight circularity.
The surface parallelism between screens and impellers is a highly critical parameter in maintaining the performance of your particle size reduction mills and equipment.
Quadro screens and impellers offer a level of precision that allows them to be situated closer together than any other replica on the market.
Without warps or abnormalities, the shear gap remains constant at every point. As the product flows through the mill, our tightly controlled shear gap aids in higher levels of throughput capacity.
Material is discharged quickly and efficiently through Quadro’s unique screen patterns, reducing residence time that leads to excessive particle interactions and unnecessary heat.
Milling machines for heat-sensitive powders
Quadro's mills, screens, and impellers provide the solution to undesirably high process temperatures in sensitive material applications. Our best modules for heat-sensitive milling include:
- The SLS - Laboratory Milling & Processing Platform
- The SDx™ Series - Production-Scale Milling and Sifting Platform
At Quadro Engineering, we understand the value of your ingredients and formulations and have over 40 years of innovation behind our parts engineering. Our unique manufacturing process produces parts of the highest quality, and your operations will run longer with unmatched batch-to-batch consistency.
With Quadro genuine parts, you will also experience increased operational uptime and a substantial return on investment in associated maintenance costs.
Genuine parts for your milling and size reduction equipment
Purchasing genuine parts from Quadro's aftermarket team will ensure that you benefit from:
- Proprietary designs optimizing process performance
- Increased capacity & longer-lasting parts
- Less operational downtime
- Consistent quality & controlled geometric tolerances
- Unmatched batch-to-batch process repeatability
- More particle size range control means less waste & rework
- Sustainable reduction in associated manufacturing & maintenance costs
(Ref: CS Heat Sensitive Materials)
Related Technical Articles:
